Plan now for
The 11th Annual PROMIS International Conference
Leveraging the Patient Voice from Clinical Decision-making to Policy: The Value of PROMIS
October 26-28 - Milwaukee
Early Bird Registration
opens May 31
Conference Program Chairs
J. Devin Peipert, PhD
University of Birmingham, UK
Anne Thackeray, PhD, PT, MPH
University of Utah, USA
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Author fees waived through 2026.
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The journal considers original educational papers, current concepts, study protocols, research manuscripts, (systematic) reviews, commentaries on articles, and letters to the editor. The journal also publishes editorials, special issues, and conference abstracts.
Register for PHO's Next Free Webinar
Understanding Minimal Important Change (MIC)
June 12, 2025 (Thursday), 10 am CT
Presenter: Caroline Terwee, PhD Amsterdam University Medical Centers
Netherlands
Moderator: Paul Klapproth, MD, Charité –Universitätsmedizin Berlin, Germany
This session will cover the concept of minimal important change (MIC) and how to use it . The advantages and disadvantages of existing methods for calculating the MIC will be presented. Plausible MIC values for PROMIS will be discussed, and ample time will be allocated for Q&A. Bring questions and get answers!
Check out the new APRO Articles "Hot off the press"
Establishing minimal clinically important difference for PROMIS physical function improvement after revascularization for peripheral artery disease
Comparison of PROMIS Profile CAT scores of stroke patients in a hospital and rehabilitation setting
New Publications
Flores AM, Shah M, Bedjeti K, Franklin PD, Peipert JD, Garcia SF, Lancki N, Webster KA, O'Connor M, Cella D. Risk of significant functional impairment across cancer diagnosis and care continuum. Cancer. 2025 Jan 1;131(1):e35571. doi: 10.1002/cncr.35571. Epub 2024 Sep 19. PMID: 39297349; PMCID: PMC11694161.
The authors looked at baseline physical function impairment in oncology patients enrolled in a pragmatic trial of engagement with cancer PROs. PROMIS measures analyzed in this study included PROMIS Physical Function, Pain Interference, and Fatigue. Overall, participants reported mild functional impairment, but 40% had moderate or severe impairment. Additionally, 17% had moderate or severe fatigue or pain interference. Impairments were generally greatest in the noncurative group. There were strong correlations between the domains, with co-occurence of symptoms. Findings support an unmet need and the importance of routine screening.
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Northrop A, Christofferson A, Umashankar S, Melisko M, Castillo P, Brown T, Heditsian D, Brain S, Simmons C, Hieken T, Ruddy KJ, Mainor C, Afghahi A, Tevis S, Blaes A, Kang I, Asare A, Esserman L, Hershman DL, Basu A. Implementation and impact of an electronic patient reported outcomes system in a phase II multi-site adaptive platform clinical trial for early-stage breast cancer. J Am Med Inform Assoc. 2025 Jan 1;32(1):172-180. doi: 10.1093/jamia/ocae190. PMID: 39158353; PMCID: PMC11648710.
The authors describe the development and implementation of an electronic patient reported outcome system to collect quality of life and adverse events as part of a phase II multi-site trial in oncology, which includes 10-year longitudinal monitoring. Measures included PROMIS Pain Interference, Sleep Disturbance, Physical Function, Anxiety, Depression, Fatigue, Cognitive Function, Social Roles, and Sexual Interest/Function. The paper describes the technology solution, operational considerations, as well as monitoring of progress. Patients who completed the initial PROs had an overall higher completion rate. Additionally, those with higher baseline social functioning were more likely to have overall higher PRO completion rates. Electronic completion did not differ by age.
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Edelen MO, Hays RD, Herman PM. Introducing the PROMIS-16 profile 1.0. Qual Life Res. 2025 Jan 20. doi: 10.1007/s11136-024-03885-9. Epub ahead of print. PMID: 39831935.
The authors introduce a series of papers in Quality of Life Research describing the PROMIS 16-item profile, which is a brief measure for pragmatic completion that assesses 8 quality of life domains: physical function, cognitive function, ability to participate in social roles, pain interference, fatigue, sleep disturbance, depression, and anxiety. It can be pragmatically useful as a screen while supporting more targeted in-depth assessment of specific domains.
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